Fatal Crash
Dupo Woman Killed in Early-Morning I-270 Crash Near I-44 in St. Louis County

Incident record
September 21, 2026
1:58 a.m.
Interstate 270 Northbound at South of Interstate 44
St Louis, St Louis County, MO
Missouri
2
Injuries reported
1 fatality
Missouri State Highway Patrol
Moderate drizzle · 72°F · 0.02 in precip · 5 mph wind
Report body
A 42-year-old woman from Dupo, Illinois, died following a two-vehicle crash on Interstate 270 Northbound south of Interstate 44 in St. Louis County, according to the Missouri State Highway Patrol's online crash report.
The crash happened around 1:58 a.m. local time, the Highway Patrol reported. Investigators said a 2013 RAM 1500 was traveling eastbound when it collided with a 2024 Freightliner Cascadia traveling northbound.
The woman sustained fatal injuries in the crash and was transported for medical treatment, according to the Highway Patrol. No additional injury information was released for other occupants involved.
Light drizzle was falling in the area at the time of the crash, according to weather data.
The crash, identified by the Highway Patrol as incident number 260402535, falls under the jurisdiction of Troop C. The Missouri State Highway Patrol is investigating.
This report will be updated as officials release more information.
Helpful links
Related resources
Missouri accident information
- Injury statute of limitations
- 5 years (From date of accident (RSMo 516.120) - one of the longest injury windows in the US.)
- Wrongful death statute of limitations
- 3 years (From date of death (RSMo 537.100).)
- Fault rule
- Missouri uses pure comparative fault: recovery is reduced by your percentage of fault but not barred.
- Citations
- RSMo 516.120 (SoL); RSMo 537.100 (wrongful death); pure comparative per Gustafson v. Benda
- Crash report agency
- Missouri State Highway Patrol traffic crash reports (online portal) for MSHP crashes; local agency otherwise.
This information is provided for general educational purposes only and is not legal advice. Consult a licensed attorney in your state for guidance about your specific situation.
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